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■Review

Challenges to success in heart failure: Cardiac cell therapies in patients with heart diseases
Pages 361-367
Hidemasa Oh, Hiroshi Ito, Shunji Sano

Deep and future insights into neuromodulation therapies for heart failure
Pages 368-372
Takuya Kishi

■Original Articles

Usefulness of anaerobic threshold to peak oxygen uptake ratio to determine the severity and pathophysiological condition of chronic heart failure
Pages 373-378
Junichi Tomono, Hitoshi Adachi, Shigeru Oshima, Masahiko Kurabayashi

Clinical characteristics of patients hospitalized for acute heart failure according to hospital arrival timing
Pages 379-383
Mitsutoshi Oguri, Hideki Ishii, Kenichiro Yasuda, Hiroshi Kawanishi, Yoshihiro Hanaki, Haruo Kamiya, Tatsuaki Matsubara, Toyoaki Murohara

The prognostic impact of uric acid in patients with severely decompensated acute heart failure
Pages 384-391
Hirotake Okazaki, Akihiro Shirakabe, Nobuaki Kobayashi, Noritake Hata, Takuro Shinada, Masato Matsushita, Yoshiya Yamamoto, Junsuke Shibuya, Reiko Shiomura, Suguru Nishigoori, Kuniya Asai, Wataru Shimizu

Risk stratification based on nutritional screening on admission: Three-year clinical outcomes in hospitalized patients with acute heart failure syndrome
Pages 392-398
Masashi Fujino, Hiroyuki Takahama, Toshimitsu Hamasaki, Kenichi Sekiguchi, Kengo Kusano, Toshihisa Anzai, Teruo Noguchi, Yoichi Goto, Masafumi Kitakaze, Hiroyuki Yokoyama, Hisao Ogawa, Satoshi Yasuda

■Original Articles

Association between epicardial adipose tissue volume and myocardial salvage in patients with a first ST-segment elevation myocardial infarction: An epicardial adipose tissue paradox
Pages 399-405
Masaomi Gohbara, Noriaki Iwahashi, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Inflammation of left atrial epicardial adipose tissue is associated with paroxysmal atrial fibrillation
Pages 406-411
Takashi Kusayama, Hiroshi Furusho, Haruka Kashiwagi, Takeshi Kato, Hisayoshi Murai, Soichiro Usui, Shuichi Kaneko, Masayuki Takamura

Prediction of contrast-induced nephropathy by the serum creatinine level on the day following cardiac catheterization
Pages 412-418
Makoto Watanabe, Yoshihiko Saito, Kazutaka Aonuma, Atsushi Hirayama, Nagara Tamaki, Hiroyuki Tsutsui, Toyoaki Murohara, Hisao Ogawa, Takashi Akasaka, Michihiro Yoshimura, Akira Sato, Tadateru Takayama, Mamoru Sakakibara, Susumu Suzuki, Kenichi Ishigami, Kenji Onoue, CINC-J study investigators

Predictors of reversible severe functional tricuspid regurgitation in patients with atrial fibrillation
Pages 419-425
Jae Yeong Cho, Kye Hun Kim, Jong Yoon Kim, Doo Sun Sim, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park

Clinical correlates and prognostic values of pseudoinfarction in cardiac light-chain amyloidosis
Pages 426-430
Lei Zhao, Jian Li, Zhuang Tian, Quan Fang

Regression of left ventricular hypertrabeculation is associated with improvement in systolic function and favorable prognosis in adult patients with non-ischemic cardiomyopathy
Pages 431-438
Masatoshi Minamisawa, Jun Koyama, Ayako Kozuka, Takashi Miura, Soichiro Ebisawa, Hirohiko Motoki, Ayako Okada, Atsushi Izawa, Uichi Ikeda

Prognostic effect of estimated glomerular filtration rate in patients with cardiogenic shock or cardiac arrest undergoing percutaneous veno-arterial extracorporeal membrane oxygenation
Pages 439-446
Norihiro Kuroki, Daisuke Abe, Toru Iwama, Kazuhiro Sugiyama, Akiko Akashi, Yuichi Hamabe, Kazutaka Aonuma, Akira Sato

Impact of alcohol intake on the relationships of uric acid with blood pressure and cardiac hypertrophy in essential hypertension
Pages 447-454
Shingo Seki, Yoshitsugu Oki, Seiko Tsunoda, Tomoyuki Takemoto, Tatsuya Koyama, Michihiro Yoshimura

Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): Study protocol for a randomized controlled trial
Pages 455-460
Takashi Kubo, Toshiro Shinke, Takayuki Okamura, Kiyoshi Hibi, Gaku Nakazawa, Yoshihiro Morino, Junya Shite, Tetsuya Fusazaki, Hiromasa Otake, Ken Kozuma, Takashi Akasaka

■Letters to the Editor

Sex differences in the association between serum uric acid and cardiac mortality in Asian patients with established coronary artery disease: A revisit of the ET-CHD registry in Taiwan, 1997–2003
Page 461
Yi-Hwei Li, Gen-Min Lin

Author's reply
Pages 461-462
Masayuki Kawabe, Akira Sato, Kazutaka Aonuma

■Review

Idiopathic ventricular arrhythmias: Relevance to the anatomy, diagnosis and treatment
Pages 463-471
Takumi Yamada

■Original Articles

Relationship between local production of microRNA-328 and atrial substrate remodeling in atrial fibrillation
Pages 472-477
Takeshi Soeki, Tomomi Matsuura, Sachiko Bando, Takeshi Tobiume, Etsuko Uematsu, Takayuki Ise, Kenya Kusunose, Koji Yamaguchi, Shusuke Yagi, Daiju Fukuda, Hirotsugu Yamada, Tetsuzo Wakatsuki, Michio Shimabukuro, Masataka Sata

Enlarged left atrium and sudden death risk in hypertrophic cardiomyopathy patients with or without atrial fibrillation
Pages 478-484
Yuichiro Minami, Shintaro Haruki, Bun Yashiro, Tsuyoshi Suzuki, Kyomi Ashihara, Nobuhisa Hagiwara

The impact of B-type natriuretic peptide levels on the suppression of accompanying atrial fibrillation in Wolff-Parkinson-White syndrome patients after accessory pathway ablation
Pages 485-491
Mihoko Kawabata, Masahiko Goya, Takamitsu Takagi, Shu Yamashita, Shinsuke Iwai, Masahito Suzuki, Tomomasa Takamiya, Tomofumi Nakamura, Tatsuya Hayashi, Atsuhiko Yagishita, Takeshi Sasaki, Yoshihide Takahashi, Yuhichi Ono, Hitoshi Hachiya, Yasuteru Yamauchi, Kenichiro Otomo, Junichi Nitta, Kaoru Okishige, Mitsuhiro Nishizaki, Yoshito Iesaka, et al.

Cryoballoon ablation for persistent atrial fibrillation – Large single-center experience
Pages 492-497
Florian Straube, Stefan Hartl, Uwe Dorwarth, Michael Wankerl, Benedikt Bunz, Ullrich Ebersberger, Ellen Hoffmann

■Original Articles

Treatment and outcomes of patients with recurrent myocardial infarction: A prospective observational cohort study
Pages 498-503
Dragana Radovanovic, Lea Maurer, Osmund Bertel, Fabienne Witassek, Philip Urban, Jean-Christophe Stauffer, Giovanni Pedrazzini, Paul Erne

Impact of final kissing balloon inflation on vessel healing following drug-eluting stent implantation: Insight from the optical coherence tomography sub-study of the J-REVERSE trial
Pages 504-511
Hachidai Takahashi, Hiromasa Otake, Toshiro Shinke, Yoshinobu Murasato, Yoshihisa Kinoshita, Masahiro Yamawaki, Yoshihiro Takeda, Kenichi Fujii, Shin-ichiro Yamada, Yoshihisa Shimada, Takehiro Yamashita, Kazuhiko Yumoto, Ken-ichi Hirata

Efficacy of combined administration of intracoronary papaverine plus intravenous adenosine 5′-triphosphate in assessment of fractional flow reserve
Pages 512-516
Takeshi Nishi, Hideki Kitahara, Yo Iwata, Yoshihide Fujimoto, Takashi Nakayama, Masayuki Takahara, Kazumasa Sugimoto, Yoshio Kobayashi

Adequate time in therapeutic INR range using triple antithrombotic therapy is not associated with long-term cardiovascular events and major bleeding complications after drug-eluting stent implantation
Pages 517-522
Hirokazu Konishi, Katsumi Miyauchi, Takatoshi Kasai, Shuta Tsuboi, Manabu Ogita, Ryo Naito, Tomotaka Dohi, Hiroshi Tamura, Shinya Okazaki, Hiroyuki Daida

Predictive factors for bleeding during treatment with rivaroxaban and warfarin in Japanese patients with atrial fibrillation – Subgroup analysis of J-ROCKET AF
Pages 523-528
Masatsugu Hori, Masayasu Matsumoto, Norio Tanahashi, Shin-ichi Momomura, Shinichiro Uchiyama, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Mary Cavaliere, Kazuma Iekushi, Satoshi Yamanaka, J-ROCKET AF Study Investigators

Circadian variations in laboratory measurements of coagulation assays after administration of rivaroxaban or warfarin in patients with nonvalvular atrial fibrillation
Pages 529-535
Yuka Hitaka, Masahiro Ogawa, Bo Zhang, Shunichiro Goto, Yoshihisa Nagata, Joji Morii, Satoshi Imaizumi, Tomoo Yasuda, Naomichi Matsumoto, Akira Matsunaga, Keijiro Saku

Predictors of surgery-induced muscle proteolysis in patients undergoing cardiac surgery
Pages 536-541
Yuki Iida, Takenori Yamazaki, Hajime Arima, Tsutomu Kawabe, Sumio Yamada

Rapid and high-dose titration of epoprostenol improves pulmonary hemodynamics and clinical outcomes in patients with idiopathic and heritable pulmonary arterial hypertension
Pages 542-547
Naoto Tokunaga, Aiko Ogawa, Hiroshi Ito, Hiromi Matsubara

Early menopause does not influence left ventricular diastolic dysfunction: A clinical observational study in healthy subjects
Pages 548-553
Megumi Hirokawa, Masao Daimon, Seitetsu L. Lee, Tomoko Nakao, Takayuki Kawata, Koichi Kimura, Tomoko S. Kato, Yoshiko Mizuno, Masafumi Watanabe, Yutaka Yatomi, Tsutomu Yamazaki, Issei Komuro

Study design of J-ELD AF: A multicenter prospective cohort study to investigate the efficacy and safety of apixaban in Japanese elderly patients
Pages 554-558
Masaharu Akao, Takeshi Yamashita, Ken Okumura, J-ELD AF Investigators

■Letters to the Editor

Coronary artery calcification and lifestyle factors   
Page 559
Tomoyuki Kawada

Author's reply   
Pages 559-560
Hideki Tashiro, Tomoki Shikada

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