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SPECTを用いた心筋血流定量の臨床的意義を概説した総論（Otaki, et al.）、高齢心不全患者におけるフレイル・サルコペニア・悪液質の実態と予後への影響を多施設前向きコホートで検討した研究FRAGILE-HFを中心とした総論（Uchida, et al.）、救急外来における急性心不全診断に対する心・肺POCUSの有用性を整理した系統的レビュー（Popat, et al.）など、心不全診療・画像診断・高齢者循環器診療などをカバーする臨床研究を掲載しております。
南野 徹〔Editor-in-Chief〕、末永 祐哉〔Chief Executive Editor〕
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Regular Articles
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🔸Review articles
- Beyond perfusion imaging: the growing clinical role of myocardial blood flow quantification by SPECT
- Yuka Otaki
- Pages 1-9
- Current findings and challenges on frailty, sarcopenia, and cachexia in older patients with heart failure: insights from the FRAGILE-HF study
- Shota Uchida, Kentaro Kamiya, Masashi Yamashita, Takumi Noda, Nobuyuki Kagiyama, Yuya Matsue
- Pages 10-16
- RNF213 and cardiovascular disease: A review of histopathological, genetic perspectives, and potential molecular mechanisms
- Toshinaru Kawakami, Masamichi Ito, Takayuki Isagawa, Takahiro Kuchimaru, Norihiko Takeda
- Pages 17-22
- Nanoparticle-driven drug delivery system for cardiovascular treatment
- Raj Patel, Dhruvi Patel, Unnati Dani, Ketan Kuperkar
- Pages 23-37
- The role of POCUS in diagnosing acute heart failure in the emergency department: A meta-analysis
- Apurva Popat, Sweta Yadav, Gauri Pethe, Ateeq Rehman, Param Sharma, Shereif Rezkalla
- Pages 38-50
- Clinical challenges in calcific mitral stenosis from diagnosis to management
- Nahoko Kato, Hiroyuki Watanabe, Patricia A. Pellikka, Mayra Guerrero
- Pages 51-60
- Antithrombotic management in catheter ablation for ventricular arrhythmias - Mini review
- Kanae Hasegawa, William G. Stevenson
- Pages 61-63
- Perivascular adipose tissue in cardiovascular disease: From mechanisms to therapeutic targets
- Kazutaka Ueda
- Pages 64-68
- Pressure-volume loop analysis in heart failure with preserved ejection fraction: Implications for cardiac mechanics, diagnosis, and treatment strategy
- Naoki Fujimoto, Taku Omori, Keishi Moriwaki, Shiro Nakamori, Kaoru Dohi
- Pages 69-76
- Cardiopulmonary neuro-immune reflex: From afferent stress signaling to peripheral myeloid memory
- Junichi Sugita, Ziyu Chen, Naoto Setoguchi, Kohsaku Goto, Atsushi Kobayashi, Kunihiko Kani, Yiyi Yang, Jiaxin Ku, Kensuke Ueno, Ryoko Uchida, Eriko Hasumi, Tsukasa Oshima, Yukiteru Nakayama, Katsuhito Fujiu
- Pages 77-84
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🔸Original articles
- Clinical characteristics and outcomes of hospitalized patients with heart failure from the Japanese prospective registry
- Nobuyuki Enzan, Takeshi Tohyama, Tatsuya Watanabe, Takuya Nagata, Eri Noda, Yoshitomo Tsutsui, Masataka Ikeda, Takafumi Sakamoto, Shouji Matsushima, Yuya Matsue, Takeshi Kitai, Tatsunori Taniguchi, Keisuke Kida, Takahiro Okumura, Takuya Kishi, Tomomi Ide, Hiroyuki Tsutsui
- Pages 85-91
- Real-world safety of sacubitril/valsartan in Japanese patients with chronic heart failure: A post-marketing surveillance study
- Jiro Arita, Tomomi Ohishi, Takayoshi Sasajima, Daisuke Yarimizu, Katsuya Onishi
- Pages 92-101
- Characteristics of anxiety about returning to work after implantable cardioverter defibrillator implantation in Japan
- Yasunobu Yamagishi, Taichi Watabe, Daiki Nakahara, Kazunari Taniguchi, Yasushi Oginosawa, Masaharu Kataoka
- Pages 102-107
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🔸Research Letter
- Combination therapy with SGLT2-inhibitors and tafamidis in transthyretin cardiomyopathy
- Kevin Chung, Ramzi Ibrahim, Mahmoud Abdelnabi, Hoang Nhat, Eiad Habib, Mohamed Allam, Hossam Elbenawi, Nima Baba Ali, Juan Farina, Balaji Tamarappoo, Justin Z. Lee, Chadi Ayoub, Kwan Lee, D. Eric Steidley, Dan Sorajja, Julie Rosenthal, Talal Hilal, Reza Arsanjani
- Pages 108-110
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🔸Letter to the Editors
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🔸Case Reports
- A rare case of left ventricular cardiac rupture in the acute phase of takotsubo syndrome
- Shu Iwata, Shoichiro Yatsu, Jun Shitara, Hirohisa Endo, Hideki Wada, Manabu Ogita, Satoru Suwa
- Pages 1-5
- Long-term follow-up of patients with catecholaminergic polymorphic ventricular tachycardia related to a novel CALM2 variant
- Seiko Ohno, Koichi Kato, Megumi Fukuyama, Keiichi Hirono, Kunihiro Nishida, Minoru Horie
- Pages 6-8
- Total clinical course of left insular stroke-induced bradycardia --tachycardia and takotsubo syndrome: A case report of stroke-- heart syndrome
- Keisuke Kawai, Yusuke Kihara, Hajime Iguchi, Masaharu Ishihara, Minoru Kishi, Masahide Iwai, Hiroya Sakuramoto
- Pages 9-12
- Multidisciplinary care and advanced therapeutics in end-stage heart failure: A case report
- Takehiro Ishimaru, Masahiro Yamamoto, Atsushi Nozuhara, Tomoko Matsuda, Chikage Kiyofuji, Kenichi Tsujita
- Pages 13-17
- Transcatheter pulmonary valve implantation for re-intervention in recurrent right ventricular outflow tract obstruction
- Babu Ezhumalai, Arun Arul David, Praveen Jeya Arulraj, Muthukumaran Chinnasamy Sivaprakasam
- Pages 18-22
- Takotsubo syndrome presenting as ventricular fibrillation cardiopulmonary arrest coupled with complete heart block
- Atsuko Hashimoto, Yuki Nishimura, Junya Komatsu, Hiroki Nakayama, Hiroki Sugane, Hayato Hosoda, Koji Nishida, Yoko Nakaoka, Shinji Mito, Ryu-ichiro Imai, Shu-ichi Seki, Sho-ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi
- Pages 23-26
- A fatal case of extensive arteriovenous malformation
- Tomoyuki Watanabe, Masumi Iwai-Takano, Rei Sekine, Yuko Hashimoto
- Pages 27-30
- Transcatheter arterialization of deep veins in a patient with no-option CLTI with thromboangiitis obliterans: A case report
- Kazuhiro Asano, Tatsuya Nakama, Shunsuke Kojima, Kotaro Obunai
- Pages 31-35
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